The University of South Dakota (USD) is a public research university in Vermillion, South Dakota. Established by the Dakota Territory legislature in 1862, 27 years before the establishment of the state of South Dakota, USD is the flagship university for the state of South Dakota and the state's oldest public university. It occupies a 274 acres (1.11 km2) campus located in southeastern South Dakota, approximately 63 miles (101 km) southwest of Sioux Falls, 39 miles (63 km) northwest of Sioux City, Iowa, and north of the Missouri River.
The university is home to South Dakota's only medical school and law school. It is also home to the National Music Museum, with over 15,000 American, European, and non-Western instruments. USD is governed by the South Dakota Board of Regents, and its president is Sheila Gestring. The university has been accredited by the North Central Association of College and Schools since 1913. It is classified among "R2: Doctoral Universities – High research activity".
University of South Dakota's alumni include a total of 17 Truman Scholars, 12 Rhodes Scholars, and 1 Nobel Laureate, (Ernest Lawrence '22, 1939 Nobel Prize in Physics.) The athletic teams compete in the NCAA's Division I as members of The Summit League, except football, which competes in the Missouri Valley Football Conference.